产品货号：
Z33358
中文名称：
BCL11A抗体
英文名称：
Anti-BCL11A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BCL11A Antibody |
| 指标别名 | B cell CLL/lymphoma 11A;B cell lymphoma/leukemia 11A;BCL11A;COUP TF interacting protein 1;CTIP1;EVI 9;EVI9;HBFQTL5;KIAA1809;ZNF856 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | BCL11A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Ctip1 Functions as a myeloid and B-cell proto-oncogene.May play important roles in leukemogenesis and hematopoiesis.An essential factor in lymphopoiesis,is required for B-cell formation in fetal liver.May function as a modulator of the transcriptional repression activity of ARP1. |
| 实际分子量 | 120KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | BCL11A is a zinc finger-containing transcriptional repressor that is important for normal hematopoiesis (1).Alternative splicing of the BCL11A transcript results in several isoforms of the protein (2).BCL11A is required for the early stages of B lineage commitment and mice lacking BCL11A fail to develop B cells (1).Mice deficient in BCL11A also fail to develop plasmacytoid dendritic cells (3).In addition,BCL11A regulates the switch from fetal to adult hemoglobin by repressing expression of fetal hemoglobin in adult erythroid cells (4).Since expression of fetal hemoglobin can decrease the severity of hemoglobin disorders in adults,BCL11A is a potential therapeutic target for these diseases (4).BCL11A was also recently identified as a component of the mammalian SWI/SNF complex (5).BCL11A is required for morphogenesis and terminal differentiation of dorsal spinal neurons (6). |
| Uniprot ID | Q9H165 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：BCL11A抗体，BCL11A单抗，Anti-BCL11A Antibody